ChronoRepair: modeling DNA repair and induction at the same time

DNA repair models that incorporate a repair “clock” are crucial in radiopharmaceutical therapy, as they account for the continuous radiation dose experienced by cells during treatment. These models consider the simultaneous processes of damage induction and repair, allowing for a more accurate prediction of cellular outcomes. By evaluating the remaining damage at specific cell cycle checkpoints, these time-sensitive models help optimize therapy effectiveness, ultimately leading to more targeted and successful cancer treatments.

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