Postdoctoral Fellow

About me: I was born in Málaga, a beautiful city located in the south of Spain. I studied at the University of Málaga, where I completed a BSc in Biomedical Engineering and afterward an MSc in Mathematics.  Because I was intrigued by how physics can help us understand biological processes, I decided to dive into research. In this line, I did my Ph.D. at the University of Navarra (Pamplona, Spain), and currently, I am doing my Postdoc at Massachusetts General Hospital (Boston, US). 

Research Interests: My research interests are related to medical physics/biophysics. Especially, I am very interested in the development of computational models for improving decision-making in the clinic.  During my Ph.D., my research was focused on lung adaptive radiotherapy, and currently, I am working with Y-90 radioembolization for liver cancer. Other research lines, such as radiopharmaceuticals and their radiobiological effect, as well as the modeling of tumor microvasculature, are of great interest to me.

• 2024 – Most International Citizen Award for Outstanding Health Research. COPE Málaga.
• 2024 – John B. Little Award for Best Poster Presentation. Harvard T.H Chan, School of Public Health.
• 2024 – Selected for the Leadership Development Program for Researchers organized by the Mass General Hospital and Harvard Medical School.
• 2023 – Best Medical / AAPM Travel Fellowship.
• 2023 – Scholars and Trainees Travel Award in the 17^th International Congress for Radiation Research.
• 2023 – Best in Physics (Therapy) Distinction in the American Association of Physicists in Medicine Annual Meeting & Exhibition.
• 2019 – Top abstract in the XII Conference on Research in Experimental and Health Sciences. University of Navarra.

• García-Cardosa M, Meiriño R, Calvo FA, Antolín E, Aguilar B, Vidorreta M, Cuevas R, Barbés B, Huesa-Berral C, Azcona JD, Burguete J. “FLIP: a novel method for patient-specific dose quantification in circulating blood in large vessels during proton or photon external beam radiotherapy treatments.” Physics in Medicine and Biology, November 11, 2024, https://doi.org/10.1088/1361-6560/ad8ea5.
• Huesa-Berral C, Terry JF, Kunz L, Bertolet A. Sequencing microsphere selective internal radiotherapy after external beam radiotherapy for hepatocellular carcinoma: proof of concept of a synergistic combination. British Journal of Radiology. 2024. https://doi.org/10.1093/bjr/tqae209
• Bobić, M*, Huesa-Berral C*, Terry JF, Kunz LV, Schuemann J, Fisher DR, Maitz C, and Bertolet A. “Monte Carlo Dosimetric Analyses on the Use of ⁹⁰ Y-IsoPet Intratumoral Therapy in Canine Subjects.” Physics in Medicine & Biology, July 25, 2024. https://doi.org/10.1088/1361-6560/ad67a4. * Share first authorship.
• Huesa-Berral C, Withrow JD, Dawson RJ, Beekman C, Bolch WE, Paganetti H, Wehrenberg-Klee E, and Bertolet A. “MIDOS: A Novel Stochastic Model towards a Treatment Planning System for Microsphere Dosimetry in Liver Tumors.” European Journal of Nuclear Medicine and Molecular Imaging, 51, no. 6 (May 2024): 1506–15. https://doi.org/10.1007/s00259-023-06567-9.
• Arce P., Lagares, JI., Azcona JD, Huesa-Berral, C., Burguete J. Precise dosimetric comparison between GAMOS/Geant4 and the collapsed cone convolution algorithm for 4D dose accumulated using deformable image registration in lung SBRT treatments. Radiation Physics and Chemistry. 2023; 208.
• Azcona JD., Aguilar B., Perales A., Irazola L., Polo R., Zucca D., Viñals A., Cabello P., Delgado JM., Pedrero D., Bermúdez R., Fayos-Sola R., Huesa-Berral C., Burguete J. Commisioning of a synchrotron- based proton beam therapy system for use with a monte carlo treatment planning system. Radiation Physics and Chemistry. 2023 (204)
• Huesa-Berral, C., Juan de la Cruz, C., van Kranen, S., Rossi M, Belderbos, J., Azcona, J. D., Burguete J., Sonke, JJ. Detailed dosimetric evaluation of inter-fraction and respiratory motion in lung stereotactic body radiation therapy based on daily 4D cone beam CT images. Phys. Med. Biol. 2022; 68(1).
• Meraviglia-Crivelli D., Villanueva H., Zheleva A., Villalba-Esparza M., Moreno B., Puravankara A., Calvo A., Cebollero J., Ruiz I., Huesa-Berral C., Pastor F. IL-6/STAT3 signaling in tumor cells restricts the expression of frameshift-derived neoantigens by SMG1 induction. Molecular Cancer. 2022. 28;21(1):211.
• Huesa-Berral, C., Burguete, J., Moreno-Jiménez, M. and Azcona, J.D. A method using 4D dose accumulation to quantify the interplay effect in lung stereotactic body radiation therapy. Phys. Med. Biol. 2021; 66(3).
• Azcona, J. D., Huesa‐Berral, C., Moreno‐Jiménez, M., Barbés, B., Aristu, J. J. and Burguete, J. A novel concept to include uncertainties in the evaluation of stereotactic body radiation therapy after 4D dose accumulation using deformable image registration. Med Phys. 2019; 46(10): 4346 – 4355.

• Huesa-Berral C., Withrow JD., Dawson RJ., Beekman C., Bolch WE., Paganetti H., Bertolet A. A novel stochastic approach to simulate the distribution of Y-90 microspheres in liver tumors. 65th Annual Meeting of the American Association of Physicists in Medicine, 2023.
• Huesa-Berral C., Burguete J., Moreno-Jiménez M., Azcona JD. A method using 4D dose accumulation to quantify the interplay effect in lunt tumor coverage. 3^rd European Congress of Medical Physics, 2021.