Carlos Huesa-Berral, Ph.D.

Postdoctoral Fellow

Member of the lab: October 2022 –

About me: I was born in Málaga, a beautiful city located in the south of Spain. I studied at the University of Málaga, where I completed a BSc in Biomedical Engineering and afterward an MSc in Mathematics.  Because I was intrigued by how physics can help us understand biological processes, I decided to dive into research. In this line, I did my Ph.D. at the University of Navarra (Pamplona, Spain), and currently, I am doing my Postdoc at Massachusetts General Hospital (Boston, US). 

Research Interests: My research interests are related to medical physics/biophysics. Especially, I am very interested in the development of computational models for improving decision-making in the clinic.  During my Ph.D., my research was focused on lung adaptive radiotherapy, and currently, I am working with Y-90 radioembolization for liver cancer. Other research lines, such as radiopharmaceuticals and their radiobiological effect, as well as the modeling of tumor microvasculature, are of great interest to me.

Awards and Honors

  • Selected for the Leadership Development Program for Researchers organized by the Mass General Hospital and Harvard Medical School 2024.
  • Best Medical / AAPM Travel Fellowship. 2023.
  • Scholars and Trainees Travel Award in the 17th International Congress for Radiation Research. 2023.
  • Best in Physics (Therapy) Distinction in the American Association of Physicists in Medicine Annual Meeting & Exhibition. 2023.


  • Huesa-Berral C, Withrow JD, Dawson RJ, Beekman C, Bolch WE, Paganetti H, Wehrenberg-Klee E, Bertolet A. MIDOS: a novel stochastic model towards a treatment planning system for microsphere dosimetry in liver tumors. Eur J Nucl Med Mol Imaging. 2023 Dec 29. doi: 10.1007/s00259-023-06567-9. Epub ahead of print. PMID: 38155237.
  • Arce P., Lagares, JI., Azcona JD, Huesa-Berral, C., Burguete J. Precise dosimetric comparison between GAMOS/Geant4 and the collapsed cone convolution algorithm for 4D dose accumulated using deformable image registration in lung SBRT treatments. Radiation Physics and Chemistry. 2023; 208.
  • Azcona JD., Aguilar B., Perales A., Irazola L., Polo R., Zucca D., Viñals A., Cabello P., Delgado JM., Pedrero D., Bermúdez R., Fayos-Sola R., Huesa-Berral C., Burguete J. Commisioning of a synchrotron- based proton beam therapy system for use with a monte carlo treatment planning system. Radiation Physics and Chemistry. 2023 (204)
  • Huesa-Berral, C., Juan de la Cruz, C., van Kranen, S., Rossi M, Belderbos, J., Azcona, J. D., Burguete J., Sonke, JJ. Detailed dosimetric evaluation of inter-fraction and respiratory motion in lung stereotactic body radiation therapy based on daily 4D cone beam CT images. Phys. Med. Biol. 2022; 68(1).
  • Meraviglia-Crivelli D., Villanueva H., Zheleva A., Villalba-Esparza M., Moreno B., Puravankara A., Calvo A., Cebollero J., Ruiz I., Huesa-Berral C., Pastor F. IL-6/STAT3 signaling in tumor cells restricts the expression of frameshift-derived neoantigens by SMG1 induction. Molecular Cancer. 2022. 28;21(1):211.
  • Huesa-Berral, C., Burguete, J., Moreno-Jiménez, M. and Azcona, J.D. A method using 4D dose accumulation to quantify the interplay effect in lung stereotactic body radiation therapy. Phys. Med. Biol. 2021; 66(3).
  • Azcona, J. D., Huesa‐Berral, C., Moreno‐Jiménez, M., Barbés, B., Aristu, J. J. and Burguete, J. A novel concept to include uncertainties in the evaluation of stereotactic body radiation therapy after 4D dose accumulation using deformable image registration. Med Phys. 2019; 46(10): 4346 – 4355.

Conference talks

  • Huesa-Berral C., Withrow JD., Dawson RJ., Beekman C., Bolch WE., Paganetti H., Bertolet A. A novel stochastic approach to simulate the distribution of Y-90 microspheres in liver tumors. 65th Annual Meeting of the American Association of Physicists in Medicine, 2023.
  • Huesa-Berral C., Burguete J., Moreno-Jiménez M., Azcona JD. A method using 4D dose accumulation to quantify the interplay effect in lunt tumor coverage. 3rd European Congress of Medical Physics, 2021.
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