Clinical Medical Physicist / Visiting Ph.D. Student

About me: I received my degree in Physics from Universitat de Barcelona in 2006 and subsequently completed a Medical Physics residency program at Hospital Universitario Virgen Macarena between 2007 and 2010. Since then, I have accrued over ten years of professional experience as a Clinical Medical Physicist within the Andalusian Health System. My professional focus is primarily on radiotherapy, including treatment planning, machine and patient quality assurance, radiation dosimetry, and more. I am also keenly interested in image processing, computer simulation (particularly Monte Carlo simulations), software development, and data science.

Research Interests: From the early stages of my career in medical physics, I have consistently been involved in developing computational tools to address a wide array of radiation-related problems. I have established Monte Carlo-based models for dosimetric characterization of various radiation sources, such as LINACs and brachytherapy seeds, and for treatment verification. A key outcome of this work is the CloudMC project – a cloud computing application specifically designed for Monte Carlo verification of radiotherapy treatments. As the Principal Investigator of two publicly funded projects, I have been integral to the development and implementation of CloudMC in the clinical workflow at Virgen Macarena Hospital in Seville. Most recently, my research has been focused on radiation therapy for eye tumors. In this capacity, I have developed a Monte Carlo-based calculation system and am currently investigating the potential use of metallic nanoparticles as radiation enhancement agents.

• Miras H, Terron JA, Bertolet A, Leal A. Modified geometry of 106Ru asymmetric eye plaques to improve dosimetric calculations in ophthalmic brachytherapy. J Pers Med. 2022. doi: 10.3390/jpm12050723
• Miras H, Ortiz A, Bertolet A, Terron JA. A Monte Carlo dose calculation system for ophthalmic brachytherapy based on a realistic eye model. Med Phys. 2021. doi: 10.1002/mp.15045
• Bertolet A, Wals A, Miras H, Macias J. Organic generation of real-world data for clinical evidence in radiation oncology. Int Jour Med Inf. 2020. doi: 10.1016/j.ijmedinf.2020.104301
• Miras H, Jimenez R, Perales A, Terron JA, Bertolet A, Ortiz A, Macias J. Monte Carlo verification of radiotherapy treatments with CloudMC. Rad. Onc. 2018; 13:99. doi 10.1186/s13014- 018-1051-9
• Miguez C, Jimenez-Ortega E, Palma Bianey, Miras H, Ureba A, Arrans A, Carrasco F, Illescas A, Leal A. Clinical implementation of combined modulated electron and photon beams with conventional MLC for accelerated partial breast irradiation. Radiother Oncol. 2017;124(1):124-129. doi:10.1016/j.radonc.2017.06.011
• Perales A, Cortés-Giraldo MA, Miras H, Arrans A, Gallardo MI. Dosimetric impact assessment using a general algorithm in Geant4 simulations for a complex-shaped multileaf collimator. Phys Med. 2017; 41:39-45. doi:10.1016/j.ejmp.2017.03.026
• Battaglia MC, Schardt D, Espino J, Gallardo MI, Cortés-Giraldo MA, Quesada JM, Lallena AM, Miras H, Guirado D. Dosimetric response of radiochromic films to protons of low energies in the Bragg peak region. Phys. Rev. Accel. Beams. 2016;19(6):064701(1)-(7). doi:10.1103/PhysRevAccelBeams.19.064701
• Ureba A, Salguero FJ, Barbeiro AR, Jimenez-Ortega E, Ureba A, Baeza JA, Miras H, Linares R, Perucha M, Leal A. MCTP system model based on linear programming optimization of apertures obtained from sequencing patient image data maps. Med Phys. 2014;41(8):081719. doi:10.1118/1.4890602
• Zarza-Moreno M, Carreira P, Madureira L, Miras H, Salguero FJ, Leal A, Teixeira N, Jesus AP, Mora G. Dosimetric effect by shallow air cavities in high energy electron beams. Med Phys. 2014;30(2):234-41. doi:10.1016/j.ejmp.2013.07.125
• Miras H, Jiménez R, Miras C, Gomà C. CloudMC: a cloud computing application for Monte Carlo simulation. Phys. Med. Biol. 2013;58:N125-N133. doi:10.1088/0031-9155/58/8/N125
• Miras H, Terrón JA, Lallena AM.  Monte Carlo simulation of COMS ophthalmic applicators loaded with Bebig I25.S16 seeds and comparison with planning system predictions. Physica Medica. 2012; ISSN 1120-1797. doi:10.1016/j.ejmp.2012.07.003
• Miras H, Arrans R. An easy method to account for light scattering dose dependence in radiochromic films. Med. Phys. 2009; 36:3866-3900. doi:10.1118/1.3176892
• Arrans R, Miras H, Ortiz M, Terrón JA, Macías J, Ortíz A. Dosimetría con películas radiocrómicas (Radiochromic film dosimetry).  Rev. Fis. Med.  2009; 10(2):83-104.

• Miras H, Terrón JA, Bertolet A.  New geometric models for improving Monte Carlo calculations of Ru/Rh asymmetric ophthalmic applicators; 2022 April 11-13; Antwerp, Belgium.
• Miras H, Jiménez R. Moving PRIMO to the cloud.  Workshop on the Monte Carlo radiotherapy system PRIMO; 2017 September 20-22; Essen, Germany.
• Miras H, Jiménez R, Perales A, Cortes-Giraldo MA, Arrans R, Ortiz A, Macias J. Simulación Monte Carlo en la nube de tratamientos de radioterapia con CloudMC. 5 Congreso Conjunto SEFM-SEPR; 2017 June 13-16; Girona, Spain.
• Miras H, Jiménez R. CloudMC: A cloud computing platform for radiation calculations.  Clinical Genomics & Informatics; 2013 December 4-6; Lisbon, Portugal.
• Miras H, Jiménez R, Miras C. CloudMC: A cloud computing map-reduce implementation for radiotherapy. Big Data Spain; 2012 November 16; Madrid, Spain.
• Miras H, Jiménez R, Miras C,  Gomà C. CloudMC: a cloud computing application for Monte Carlo simulation. In: 3rd EWMCTP; 2012 May 16-18; Seville, Spain.
• Miras H, Dorado P, Ortiz A, Macías J. Presentación de un software para el análisis de imágenes: UTOPIA (Useful TOols for Picture and Image Analysis) (Presentation of a software for image analysis). In: Virgen Macarena Hospital 5th research meeting; 2007 November 8-10; Seville, Spain.